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The collaborative Human Challenge study is the first in the world to perform detailed monitoring over the full course of COVID-19, from the moment a person first encounters SARS-CoV-2, throughout the infection to the point at which the virus is apparently eliminated. The Human Challenge Programme is a partnership between Imperial College London, the Vaccine Taskforce and Department of Health and Social Care (DHSC), hVIVO (part of Open Orphan plc.), and the Royal Free London NHS Foundation Trust.

Health

How deliberately giving people illnesses is supercharging medicine

The covid-19 pandemic opened the door to once-controversial human challenge trials. Now, volunteers are willingly catching norovirus and influenza to reveal how our immune systems really fight back

Features

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Walking 3000 steps a day seems to slow Alzheimer's-related decline

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Stem cell therapy lowers risk of heart failure after a heart attack

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Men may have to exercise more than women to get same heart benefits

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Health

Wegovy has heart health benefits even if weight loss is minimal

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What’s my Alzheimer’s risk, and can I really do anything to change it?

Health

What’s my Alzheimer’s risk, and can I really do anything to change it?

Features

Health

Starting HRT in early menopause may reduce women's risk of Alzheimer's

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Two people's faces are shown, chin to chin, with their heads tilted back. A firefighter stands on the face of the person on the left, spraying a hose that is hooked up to the nose of the person on the right,

Health

Can a strange new treatment finally relieve chronic sinus infections?

Features

Health

Florida's anti-vaccine push leads dangerous shift for US public health

Analysis

Health

Covid-19 seems to age blood vessels – but only among women

Women's arteries seem to be stiffer if they have had covid-19, with the same effect not being found among men

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Vanishing Y chromosomes seem to be driving heart disease in men

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A new measure of health is revolutionising how we think about ageing

Features

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Low dose of lithium reverses Alzheimer's symptoms in mice

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The world is losing major ground in the fight against measles

Analysis