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Your genes may influence how much fruit, fish or salt you eat

Nearly 500 regions of the human genome appear to directly impact your dietary intake by affecting perception of flavours and food preferences

By Soumya Sagar

22 July 2023

Opting for fruit over other snacks may be in your genes

alvarez/E+/Anja Burgar/Getty Images

Whether you crave salty dishes or snack on fruit, your genes may influence the food choices you make. Gaining a better understanding of how this varies from person to person could one day lead to bespoke food plans that help people make nutritious choices by taking into account their genetic preferences.

鈥淒ietary intake is influenced by so many other factors – like socioeconomic status, culture and disease diagnoses – that teasing apart the direct genetic component from the environmental or indirect genetic components intrigued me,鈥 says at the University of Colorado.

聽that are associated with various aspects of a person鈥檚 dietary intake, including how much fruit, vegetables, meat and fish they eat.

The team wanted to better understand if these regions directly or indirectly influence a person鈥檚 food choices. 鈥淔or example, genes that impact diabetes risk may also be associated with dietary intake due to disease management changes, like eating less sugar, and not because the gene is directly influencing someone鈥檚 eating behaviour,鈥 says Cole.

The researchers carried out a so-called phenome-wide association study for the 814 regions. This involves taking a single genetic variant and scanning it for certain traits 鈥 such as taste preferences, eating habits and health conditions – to see if there is an association. Each region was scanned for more than 4000 traits, using data from around 500,000 participants of the UK Biobank study.

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From this, the researchers identified 481 regions in the genome that appear to directly affect dietary intake through flavour perceptions and preferences. The work was presented at , the annual meeting of the American Society for Nutrition in Boston, Massachusetts. Some of the foods and drinks that are most affected by these genes include salt, water, fish, alcohol and fruit.

鈥淐onsumers report flavour as the primary driver of food choice, therefore, identifying how different people experience different flavours may be the key to personalised nutrition to improve healthy eating,鈥 says Cole.

鈥淚鈥檓 focusing now on identifying these sensory genes involved in dietary intake and understanding how different people with different gene versions of these taste and smell receptors have different pleasure and reward activation in the brain. The goal is to make eating healthier easier for different people and I think flavour is key.鈥

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