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Health

Gene-replacement therapies are transforming children鈥檚 lives

Several therapies to correct severe genetic disorders have been approved by medical regulators in 2022, and others have produced impressive clinical trial results

By Alice Klein

23 December 2022

DNA

Gene-replacement therapies involve replacing DNA that doesn’t work properly

Shutterstock/SWKStock

This year has been full of good news stories about gene-replacement therapies alleviating severe genetic disorders in children, suggesting they are finally living up to their promise after a bumpy few decades.

鈥淲e鈥檙e curing kids of fatal diseases. It鈥檚 wonderful,鈥 聽at the University of California, Los Angeles told New 女生小视频 in May after successfully using a gene-replacement therapy to reverse a rare life-threatening immune condition called leukocyte adhesion deficiency in nine children.

Gene-replacement therapies are used to correct genetic disorders that are caused by mutations in…

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