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Microbe somehow survives without key proteins for replicating its DNA

By Michael Marshall

23 March 2021

DNA replication

To copy DNA, the enzymes helicase (red) and polymerase (blue) are usually needed

EQUINOX GRAPHICS/SCIENCE PHOTO LIBRARY

AT FIRST sight, it shouldn鈥檛 be alive: a single-celled organism that lacks most of the molecular equipment needed to kick-start DNA replication.

Duplicating DNA is fundamental to reproduction, so DNA replication systems were thought to be present in all non-parasitic species with complex cells. But it seems they aren鈥檛.

鈥淚 was astonished,鈥 says Dayana Salas-Leiva at Dalhousie University in Halifax, Canada. The microbe, Carpediemonas membranifera, must have a mechanism for copying its DNA that is unknown to science.

颁.听尘别尘产谤补苍颈蹿别谤补

Article amended on 24 March 2021

We clarified the role the missing proteins play in DNA replication

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