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Cultivating a taste for addiction?

Tobacco industry researchers have had a long-standing interest in the
addictive properties of nicotine, a US Congressional committee alleged last
week.

Tobacco companies say they do not manipulate nicotine levels in cigarettes
to keep smokers addicted, and are interested in nicotine only as a flavouring.
In hearings before the House subcommittee on health and environment last
week, Thomas Sandefur, chairman of the British-owned company Brown &
Wil-liamson, continued to maintain that position. 鈥楥onsumers tell us, when
we ask them why they didn鈥檛 smoke the denicotinised brands, that they didn鈥檛
taste very good,鈥� he said.

The subcommittee listed 26 papers written by researchers working for
Brown & Williamson or its parent company, British American Tobacco 鈥�
now BAT Industries. The papers鈥� titles include 鈥楢 Tentative Hypothesis on
Nicotine Addiction,鈥� and 鈥楴icotine in Smoke and Human Physiological Response鈥�.
The research topics include how nicotine is absorbed into the bloodstream
and how it changes brain wave patterns.

鈥榃hat all this shows is that Brown & Williamson has had an intense
interest for decades in the pharmacological effects of nicotine,鈥� said Henry
Waxman, a Democrat from California who chairs the subcommittee. 鈥榃hat does
taste have to do with brain wave alpha rhythms?鈥�

One study, called 鈥楶roject Wheat,鈥� examined the motivation for smoking.
It postulated an 鈥榠nner need鈥� among smokers, and found that the 鈥榠nner need鈥�
was best met by smoke with a relatively high nicotine content. The study,
carried out in 1976, concluded there might be a market for a cigarette that
was low in tar, but high in nicotine. Waxman said Brown & Williamson
introduced its Barclay cigarette, a low-tar brand that an independent researcher
found had high levels of nicotine, only a few years later. Normally, as
tar levels fall, so do nicotine levels. Sandefur said he was not familiar
with 鈥楶roject Wheat鈥�, or with most of the research the Congressmen asked
about, and was not around when Barclay was introduced.

He did, however, criticise David Kessler, head of the Food and Drug
Administration, who had earlier told the subcommittee that Brown & Williamson
had bred a high-nicotine strain of tobacco and used it in low-tar brands.
Sandefur said although the plant had a high nicotine level 鈥� about 6 per
cent compared with about 2.5 per cent for most domestic varieties 鈥� it was
no higher than some types of commonly used Oriental tobacco.